2021 International Congress of Diabetes and Metabolism

Plenary lecture 1	11:30~12:00 / Friday 8 September LIVE Channel A Chairman:Kun-Ho Yoon	Overview
Prof Samuel N. Breit is a clinical Immunologist and Immunopathologist at St Vincent’s Hospital Sydney and UNSW Sydney. He has a career-long interest in biomedical research and has published over 160 papers in peer-reviewed journals. He first discovered and characterized the divergent TGF-b superfamily cytokine MIC-1/GDF15 over a decade ago, and now, MIC-1/GDF15 diagnostic technology can be used in the diagnosis and management of cancer and cardiovascular disease, while therapeutic applications include the treatment of inflammatory diseases, obesity, and cancer-associated syndromes. Currently, his research is focused on understanding the central and peripheral mechanisms by which MIC-1/GDF15 causes anorexia, modulates metabolism, and impacts inflammation and immunity. Prof. Samuel Briet will provide the latest knowledge and future clinical application of the role of the GDF 15-GFRAL pathway in metabolic disorders.
Samuel N Breit The University of New South Wales, Australia	PL1The GDF15-GFRAL pathway in metabolic regulation

Plenary lecture 2	11:40~12:20 / Saturday 9 October LIVE Channel A Chairman:Jeong-Taek Woo	Overview
Prof. Myung-Shik Lee is a senior investigator at Yonsei University College of Medicine. His primary research interest is in understanding the role of autophagy in metabolic disease. Autophagy is a critical intracellular process of turnover and rejuvenation of organelles and proteins. However, until he published a paper of beta cell-specific autophagy knockout mice, no one had studied the role of autophagy in body metabolism or metabolic disorders such as type 2 diabetes. Prof. Myung-Shik Lee is a world-leading scientist, striving to understand the key molecular mechanisms involved in autophagy, apoptosis, and inflammation/immunity in diabetes. In this lecture, He will elucidate the mechanism by which autophagy, lysosome, and metabolic inflammation work in beta cells and discuss how MSL-7, an autophagy enhancer, plays a protective role in the beta cell death.
Myung-Shik Lee Yonsei University, Korea	PL2 Death of pancreatic ß-cells and death-associated inflammation in diabetes - effect of autophagy enhancer on human-type diabetes

Plenary lectures